Substances that can cause adverse health effect including but not limited to humans, aquatic and other animals such as poisoning, breathing problems, skin rashes etc. Based on such effects currently they can be classified under the categories of persistent, bioaccumulative and toxic (PBT), very persistent and very bioaccumulative (vPvB), carcinogenic, mutagenic and toxic for reproduction (CMR), or endocrine disruptors (ED). |